The lymphatic system has a vital role in the body by regulating the immune system, which protects the body against infection. It transports nutrients to cells and eliminates metabolic wastes, toxins and excess fluid from the body and stimulating vital immune defences. Lymphatic flow is readily encouraged and stimulated by several methods including exercise and stretching, elevation of extremities, lymphatic massage and hydrotherapy with hot and cold applications. Blood flow to the spleen can be enhanced by berberine, the alkaloid found in barberry, oregan grape and goldenseal.